Journal of Lipids / 2024 / Article / Tab 1 / Research Article
Plasma Lipidomics Profiling to Identify the Biomarkers of Diagnosis and Radiotherapy Response for Advanced Non-Small-Cell Lung Cancer Patients Table 1 More than twofold declined lipid elements of NSCLC patients in pre-RT, RT, and post-RT groups with statistical significance, as compared with healthy control (
or less).
Pre-RT/Con RT/Con Post-RT/Con Elements Fold change Elements Fold change Elements Fold change MAG 22 : 3 0.001 <0.001 MAG 20 : 2 0.001 <0.001 MAG 22 : 0 0.002 <0.001 MAG 22 : 0 0.002 <0.001 MAG 22 : 0 0.002 <0.001 MAG 22 : 3 0.002 <0.001 MAG 20 : 0 0.002 <0.001 27 OH cholesterol 0.002 0.006 27 OH cholesterol 0.002 0.007 MAG 20 : 2 0.002 <0.001 MAG 20 : 4 0.002 <0.001 MAG 22 : 5 0.002 <0.001 MAG 20 : 1 0.003 <0.001 MAG 22 : 6 0.003 0.006 MAG 20 : 4 0.002 <0.001 27 OH cholesterol 0.003 0.016 Cholesterol 0.003 <0.001 MAG 22 : 6 0.002 0.008 MAG 22 : 6 0.003 0.008 MAG 22 : 4 0.004 0.009 MAG 20 : 0 0.003 <0.001 MAG 22 : 1 0.003 <0.001 MAG 18 : 2 0.005 0.002 MAG 20 : 2 0.003 <0.001 Cholesterol 0.003 <0.001 MAG 22 : 5 0.007 <0.001 MAG 20 : 3 0.003 0.004 MAG 18 : 0 0.006 0.009 MAG 20 : 1 0.008 <0.001 MAG 20 : 1 0.003 <0.001 MAG 18 : 1 0.007 0.001 MAG 22 : 1 0.008 0.002 MAG 22 : 4 0.003 0.002 MAG 22 : 5 0.021 <0.001 MAG 20 : 0 0.010 <0.001 Cholesterol 0.003 <0.001 MAG 20 : 4 0.022 <0.001 MAG 22 : 3 0.010 <0.001 MAG 22 : 1 0.003 <0.001 MAG 22 : 2 0.023 0.001 MAG 22 : 2 0.015 0.001 MAG 22 : 2 0.003 <0.001 MAG 22 : 4 0.039 0.004 MAG 18 : 1 0.015 0.008 MAG 18 : 2 0.004 0.001 MAG 18 : 2 0.061 0.006 MAG 18 : 0 0.016 0.005 MAG 18 : 0 0.005 0.001 PS (18 : 1/22 : 4) 0.298 <0.001 FFA(24 : 0) 0.312 <0.001 MAG 18 : 1 0.006 0.001 FFA (24 : 0) 0.336 <0.001 PS (18 : 1/22 : 4) 0.313 <0.001 PS (18 : 1/22 : 4) 0.215 <0.001 PI (18 : 1/20 : 2) 0.410 0.029 PS (14 : 0/20 : 5) 0.347 0.007 FFA (24 : 0) 0.251 <0.001 PG (20 : 0/18 : 3) 0.417 0.001 PI (18 : 2/22 : 4) 0.386 0.003 PI (18 : 1/20 : 2) 0.305 0.022 PI (20 : 0/20 : 5) 0.424 0.032 PG (18 : 1/18 : 3) 0.438 0.001 PI (18 : 0/20 : 1) 0.350 0.007 PG (18 : 1/18 : 3) 0.429 0.001 PG (20 : 0/20 : 3) 0.458 0.012 LPG (20 : 0) 0.393 0.047 PI (18 : 2/22 : 4) 0.433 0.001 PS (16 : 0/22 : 6) 0.471 0.002 PI (18 : 2/22 : 4) 0.418 0.002 PS (18 : 0/22 : 6) 0.437 0.002 PG (20 : 0/20 : 2) 0.475 0.028 PG (18 : 0/22 : 6) 0.430 0.001 PG (20 : 0/20 : 1) 0.461 0.022 PI (20 : 0/22 : 6) 0.445 0.030 PI (20 : 0/22 : 6) 0.466 0.028 PG (20 : 0/20 : 1) 0.469 0.033 PI (16 : 0/16 : 0) 0.471 0.006 PS (14 : 0/20 : 5) 0.498 0.032 PA (14 : 0/18 : 3) 0.480 0.012 PI (18 : 2/20 : 5) 0.484 0.003 PS (14 : 0/20 : 3) 0.494 0.028
NSCLC: non-small-cell lung cancer; pre-RT: preradiotherapy; RT: radiotherapy; post-RT: postradiotherapy.
