Plasma Lipidomics Profiling to Identify the Biomarkers of Diagnosis and Radiotherapy Response for Advanced Non-Small-Cell Lung Cancer Patients

Table 3

More than twofold declined or elevated lipid elements of NSCLC patients in pre-RT, RT, or post-RT groups with statistical significance, as compared with each other ( or less).

RT/pre-RT			Post-RT/pre-RT			Post-RT/RT
Elements	Fold change	value	Elements	Fold change	value	Elements	Fold change	value
PS (14 : 0/20 : 5)	0.433	0.010	PS (14 : 0/22 : 5)	0.425	0.001	PA (18 : 2/22 : 5)	0.386	0.025
PS (14 : 0/22 : 5)	0.488	0.020	PG (18 : 2/20 : 5)	0.481	0.020	MAG 20 : 1	0.387	0.032
PA (14 : 0/20 : 2)	2.243	0.038	PI (18 : 2/20 : 1)	2.038	0.007	PA (14 : 0/20 : 2)	0.426	0.025
PA (18 : 1/20 : 2)	2.254	0.050	PS (14 : 0/20 : 3)	2.230	0.029	LPS (18 : 1)	0.443	0.019
PA (14 : 0/18 : 3)	2.832	0.020	PA (16 : 0/18 : 1)	2.281	0.021	LPG (20 : 0)	0.470	0.003
MAG 22 : 3	8.515	0.050				PA (18 : 2/18 : 2)	0.472	0.021
						PI (18 : 0/20 : 1)	0.474	0.044
						PG (18 : 1/22 : 6)	2.017	0.024

NSCLC: non-small-cell lung cancer; pre-RT: preradiotherapy; RT: radiotherapy; post-RT: postradiotherapy.