|
| Patent number | Title | Applicant/inventor | Publication date | Lipid components | Application area | Proposed administration route | References |
|
| US20220054416A1 | Nanostructured lipid carriers and stable emulsions and uses thereof | Infectious Disease Research Institute, Seattle, WA (US) | 24.02.2022 | Capric/caprylic triglyceride, vitamin E, lauroyl polyoxylglyceride, trimystin, polyethylene glycol | Immunogenic | Intramuscular | [211] |
| US11141377B2 | Nanostructured lipid carriers and stable emulsions and uses thereof | Infectious Disease Research Institute, Seattle, WA (US) | 12.10.2021 | 313-[N–(N′,N′-Dimethylaminoethane)-carbamoyl]Cholesterol (DC cholesterol) | Immunogenic | Intramuscular | [212] |
| CN108853056B | Folic acid-targeted modification carried doxorubicin hydrochloride and gambogic acid nanostructure lipid carrier preparation and preparation method thereof | Tianjin University of Traditional Chinese Medicine | 14.09.2021 | Stearic acid, behenic acid, glyceryl behenate, glyceryl monostearate, isopropyl palmitate, isopropyl myristate, soybean oil, and oleic acid | Anticancer | Oral | [213] |
| AU2021106678A4 | A method of preparation of trimcinolone acetonide encapsulated NLCs for psoriasis treatment | Madhulika Pradhan, K. K. Sahu, Deependra Singh, Manju Rawat Singh, Krishna Yadav | 16.12.2021 | Docosahexaenoic acid (DHA), cetostearyl alcohol (CSA), poloxamer 188 | Antipsoriatic activity | Transepidermal | [214] |
| BR102019026730A2 | Antimicrobial nanostructured lipid carriers | Simone Ramos De Castro, Eneida De Paula, Talita Cesarim Mendonça Lígia, Nunes De Morais, Ribeiro Marcelo, Lancellotti Márcia Cristina, Breitkreitz | 29.06.2021 | Beeswax, tucumã butter and ucuuba butter, sesame oil, andiroba oil, copaiba oil, and rosemary oil | Antimicrobial | Oral | [215] |
| WO2019068161A1 | Method for obtaining nanostructured lipid carriers, NLCs obtained and the use thereof | Nádia Araci Bou Chacra, Paulo Cesar Cotrimlis, Marie Monteiro Nikoletta, Fotaki Raimar Löbenberg | 11.04.2019 | Hydrogenated palm oil, hydrogenated coconut mono, di, and triglycerides, stearoyl macrogol-32-glycerides | Antileishmaniasis | Oral | [216] |
| WO2018232257A1 | Nanostructured lipid carriers and stable emulsions and uses thereof | Christopher B. Fox, Amit Praful Khandhar, Neal Van Hoeven, Jesse H. Erasmus, Susan S. Lin | 20.12.2018 | Murumuru seed butter, bis-diglyceryl polyacyladipate-2 | Skin care application | Topical | [217] |
| CN104367549A | Psoralen-doxorubicin-loaded composite nanostructured lipid carrier preparation and preparation method thereof | Liaoning University | 12.09.2017 | Stearic acid, cholesterol, palmic acid, Labrasol, Miglyol 812N | Antitumor activity | Topical | [218] |
| CA2963872A1 | Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases | Anna Rita, Blanco Maria Luisa, Bondi’gennara, Cavallaro Grazia, Maria Letizia, Consoli Emanuela Fabiola, Craparo Gaetano, Giammona Mariano, Licciardi Giovanna, Pitarresi Giuseppe, Granata Patrizia, Saladino Clara, La Marca Irene, Deidda Salvatore, Papasergi Patrizia, Guarneri Salvatore, Cuzzocrea Emanuela, Esposito Santa Viola | 14.04.2016 | Tristearin, tripalmitin, caprylic/capric acid triglycerides, Compritol HD-5-ATO | Ocular diseases | Ophthalmic | [219] |
| US20160015703A1 | Nano-micro delivery systems for oromucosal delivery of an active ingredient | Ioannis S. Chronakis, Lars Jorgensen, Maria Ahlm Mattebjerg | 21.01.2016 | Nicotine | Analgesic | Oral mucosa | [220] |
| IN276/MUM/2014 | Idebenone lipid nanocarrier composition for the treatment of neurodegenerative disorders | Sachin Subhash Salunkhe, Neela Manish Bhatia, Manish Sudesh Bharia | 11.09.2015 | Glyceryl palmitostearate, propylene glycol dicaprylate/dicaprate | Neurodegenerative disorders | Oral | [221] |
| CN103263671A | Preparation and application of antitumor activator nanostructure lipid carrier | Cui Guohui, Cui Chunying, Liu Xiaozheng | 15.04.2015 | 17-Allylamino-17-demethoxygeldanamycin, glyceryl monostearate, octanoic acid/capric acid triglyceride, tween 80 | Antitumor | Topical | [222] |
| WO2015039199 | Microstructured and nanostructured pharmaceutical and veterinary compositions, containing benznidazole and derivatives thereof, which form microstructures and nanostructures in the gastrointestinal tract and biological uses thereof | Mosqueira, Vanessa Carla Furtado Oliveira, Liliam Teixeira Castanheira, Raquel Gomes | 26.03.2015 | Labrasol, Cremophor E | Antiprotozoals, chagas disease | Oral | [223] |
| CN104172184A | Quercetin nanostructured lipid carrier and preparation method thereof | Southeast University | 03.12.2014 | Polyglycereol monolaurates, tripolyglycerol monostearate, caprylic acid capric acid, camellia seed oil | Functional food field | Oral | [224] |
| WO2014123406A1 | A composition for treating leukemia | Rasedeemat Abdullahheshu, Sulaiman Rahamn Ahmad, Bustamam Abdulhow, Chee Wunyeap Swee Keong | 14.08.2014 | Zerumbone, hydrogenated palm oil, phosphatidylcholine (Lipoid S 100), and olive oil | Leukemia | Parenteral/oral | [225] |
| CN103893167A | Podophyllotoxin preparation resisting condyloma acuminata relapse and HPV latent infection | Nanfang Hospital of Southern Medical University | 02.07.2014 | Glyceryl monostearate, lecithin | HPV latent infection | Topical | [226] |
| CN103860389A | Nanostructured lipid carrier loaded with phenyl ethyl resorcinol, preparation method thereof, and cosmetic containing the same | Beinong biochemical (Suzhou Industrial Park) Co., Ltd. Suzhou Nanohealth Biotech Co., Ltd | 18.06.2014 | Glyceryl monostearate, decanoyl/octanoyl glycerides | Skincare activity | Topical | [227] |
| US20120195957A1 | Novel nanoparticle formulations for skin delivery | Mandip Singh, Sachdeva, Ram Patlolla | 06.05.2014 | Compritol 888, Miglyol 812 | Transdermal delivery, skin diseases | Topical | [228] |
| CN104688715A | Resveratrol nanostructured lipid carrier and preparation method thereof | Shanghai Traditional Chinese Medicine Hospital | 22.01.2014 | Glyceryl monolaurate, acetylation monoglyceride, Fructus persicae resin | Resveratrol-containing cosmetics | Topical | [229] |
| MYPI 2012001818 | Thymoquinone-loaded nanostructured lipid carriers (TQ-NLC) and uses thereof | Universiti Putra Malaysia | 25.10.2013 | — | Dermal diseases | Topical | [230] |
| CN102670510 | Tripterine nanostructure lipid carrier modified by lentiviral vect or and appliance for preparing and treating prostatic cancer, lung cancer, and breast cancer drug | Jiangsu Provincial Insititute of Traditional Chinese Medicine | 18.09.2013 | Tripterine, phospholipid, poloxamer 188, vitamin E, tocopherol and polyethylene glycol succinate | Breast cancer | Transdermal | [231] |
| IN422/MUM/2011 | Nanotechnology-based herbal composition for safe and effective treatment of psoriasis | Kamalinder Singh Kaur, Medha Chetan Patel | 12.07.2013 | Glycerylbehenate, trimyristin, tristearin, tripalmitin, glyceryl monostearate, cetyl alcohol, stearic acid | Antipsoriatic activity | Topical | [232] |
| CN102274187B | Nanostructural lipid carrier and preparation method and application thereof | Shanghai University of Traditional Chinese | 07.08.2013 | Glyceryl behenate-oleic acid, polyethylene glycol glyceride, glyceryl behenate-single glyceryl linoleate | — | Oral | [233] |
|
