Thyroid Cancer: Molecular and Modern Advances
1Section of Surgical Oncology and Endocrine Surgery, Boston University School of Medicine; Boston Medical Center, Boston, MA 02118, USA
2Department of Surgery, Montefiore Medical Center; Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10466, USA
3Section of Endocrinology, Diabetes and Nutrition, Department of Medicine, Boston University School of Medicine; Boston Medical Center, Boston, MA 02118, USA
Thyroid Cancer: Molecular and Modern Advances
Description
Thyroid cancer is the most common endocrine malignancy. The Statistics Epidemiology Ends Results (SEER) database indicates an increase in the incidence of thyroid cancer over the past 2 decades although the incidence of other head and neck sites has been declining. Thyroid cancer is a complex genetic disease; incorporation of recent advances in molecular genetics into treatment regimens remains a challenge. Advances in molecular markers may allow better differentiation of benign from malignant disease in thyroid nodules. We invite authors to submit original research articles as well as review articles directed at better understanding the molecular papillary pathogenesis of thyroid cancer and novel targeted therapeutic strategies in thyroid oncology. We are particularly interested in manuscripts that report the clinical applications of approved or investigational targeted therapy in thyroid cancer, molecular prognostic markers, advances in radioactive iodine treatment, surgical innovations, and diagnostic techniques. Potential topics include, but are not limited to:
- Incorporating targeted therapy in treatment for metastatic and/or recurrent papillary thyroid cancer
- Application of radioactive iodine in papillary thyroid cancer
- Surgical innovations in treatment approach to papillary thyroid cancer, especially nodal dissection
- Diagnostic innovations in papillary thyroid cancer, especially the use of ultrasound, PET/CT, or novel radiologic techniques
- Translational studies focused on assessing the clinical significance of molecular prognostic markers in papillary thyroid cancer including studies that evaluate mutations, genome-wide studies, and epigenetics
- Molecular progression model of papillary thyroid cancer
- Significance of Hurthle cells in papillary thyroid cancer
- Identification and molecular characteristics of papillary thyroid cancer stem cells
- Papillary thyroid cancer and microRNAs
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