Research Article
Beninese Plant Extracts with Antiplasmodial Activity Select New Allele Variants Msp1 and Msp2 in Plasmodium falciparum
Table 1
Msp1 and Msp2 alleles of P. falciparum detected in exposed and unexposed parasites.
| Genes | Allelic families | Fragment sizes (base pairs) per plant extract treatment | Negative control | Dissotis rotundifolia | Ehretia cymosa | Hibiscus surattensis | CpE2 | Cola millenii | Artesunate (positive control) | Costus afer |
| Msp1 | K1 | 150 | 150 | 150 | 150 | 150 | 100 | 150 | 150 | 200 | 200 | 200 | 200 | 200 | 150 | 200 | 200 | 250 | 250 | 250 | 250 | 250 | 200 | 250 | 250 | 700 | 700 | 700 | 700 | 700 | 250 | 700 | 700 | | | | | | 700 | | | Mad20 | 150 | 150 | 150 | 150 | 150 | 150 | 150 | 150 | 250 | 250 | 250 | 250 | 250 | 250 | 250 | 250 | RO33 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 700 | 300 | 300 | 700 | 700 | 300 | 700 | 700 | | 700 | 700 | | | 700 | | |
| Msp2 | 3D7 | 250 | 250 | 250 | 250 | 250 | 250 | 250 | 250 | 350 | 350 | 350 | 350 | 350 | 350 | 350 | 350 | FC27 | 180 | 150 | 180 | 180 | 180 | 180 | 180 | 180 | 900 | 180 | 300 | 300 | 300 | 300 | 400 | 300 | | 300 | 900 | 400 | 400 | 900 | 900 | 400 | | 400 | | 900 | 900 | | | 600 | | 800 | | | | | | 900 | | 900 | | | | | | |
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Values shown in the table represent the different alleles classified according to the length (in base pairs).
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