Signal Transduction in Astrocytes during Chronic or Acute Treatment with Drugs (SSRIs, Antibipolar Drugs, GABA-ergic Drugs, and Benzodiazepines) Ameliorating Mood Disorders
Figure 7
Treatment with citalopram (15 mg/kg) for 14 days (brown columns) has no effect on total GSK3β expression in hippocampus (a,b), compared to that in untreated control animals (white columns), but dramatically increases its phosphorylation (c). This effect is abolished by sulindac, an inhibitor of the stimulated pathway (green columns), from Liu et al. [82], with permission.
