Review Article

Signal Transduction in Astrocytes during Chronic or Acute Treatment with Drugs (SSRIs, Antibipolar Drugs, GABA-ergic Drugs, and Benzodiazepines) Ameliorating Mood Disorders

Figure 9

in mouse astrocytes during basal conditions control (C) and during exposure to 1 μM noradrenaline (Na) in untreated control cultures and in sister cultures which had been treated for either 7–14 days (a) or 30–45 min (b) with 1 mM lithium chloride (Li). The chronic lithium treatment decreased significantly ( ) both under basal condition and during exposure to noradrenaline (a), whereas the short-lasting exposure to Li+ had no effect, from Chen and Hertz [87].
593934.fig.009a
(a)
593934.fig.009b
(b)