Clinical Study
American Visceral Leishmaniasis: Factors Associated with Lethality in the State of São Paulo, Brazil
Table 4
Final model of factors associated with VL lethality, state of Sao Paulo, 1999–2005 (multivariate analysis).
| | Clinical outcome | | | Variable | Death | Cured | Total | OR (95% CI)* | value** | | | | | | |
| High total bilirubin | | | | | | Total Bilirubin ≥ 2.0 g/dL | 13 | 6 | 19 | 7.36 (1.65–32.76) | <0.0001 | Severe anemia | | | | | | Hemoglobin ≤ 5.0 g/dL | 7 | 13 | 20 | 4.56 (1.17–17.48) | <0.0001 | Antimicrobial agents | 34 | 59 | 93 | 5.76 (2.27–14.64) | <0.0001 | Age ≥ 50 years | 28 | 17 | 45 | 29.54 (10.6–82.6) | | Length of illness (days) | | | | | | Fever >60 days | 13 | 26 | 39 | 6.23 (2.05–18.92) | <0.0001 | Hemorrhagic manifestations | 18 | 22 | 40 | 2.62 (0.93–7.4) | 0.0001 | Cardiac abnormality | 9 | 10 | 19 | 4.73 (1.3–17.23) | <0.0001 | Diarrhea | 20 | 52 | 72 | 2.76 (1.03–7.43) | <0.0001 |
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*Odds ratio (95% confidence interval). **Likelihood ratio.
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