Research Article
Genome-Wide Prediction of Vaccine Candidates for Leishmania major: An Integrated Approach
Table 2
NetCTL predicted top scoring CTL epitopes along with start position and processing score for the HLA-A supertypes in 25 L. major candidate antigens.
| | Antigens | A1 | A2 | A3 | A24 | A26 |
| | 1 | NTDNFFFML
(228: 2.3073) | SLWSLLAGV
(127: 1.4042) | NLAAGQSLK
(489: 1.4921) | LYLLLPFLL
(19: 1.9727) | YTISLNPLL
(512: 1.6485) |
| | 2 | MSSTSFDDY
(38: 3.3876) | ALVSINVPL
(224: 1.3414) | SLFRVANCK
(238: 1.4763) | VWCTVPDCI
(421: 1.4489) | SVVDPMQNY
(409: 2.3630) |
| | 3 | CTQCAPNYY
(308: 2.8811) | LLTSFAMHL
(495: 1.0227) | SSYSCVSQK
(469: 1.6062) | GYAKDSNGF
(175: 1.5045) | YVVDSYDGL
(351: 1.4847) |
| | 4 | FIDANTAIY
(122: 3.1585) | MLPDMTCSL
(390: 1.4053) | SSYSCVSQK
(674: 1.6062) | GYIVVDKYF
(93: 1.4189) | YVVDSYDGL
(556: 1.4847) |
| | 5 | TTSTTTNTV
(68: 1.4293) | LMAAMLVAV
(7: 1.2898) | TMPTAPSSK
(43: 1.1211) | GYMPTASFK
(142: 0.8997) | ETASTTSTT
(64: 0.5879) |
| | 6 | VSAQTIDDY
(32: 2.4784) | YLCDRTTAA
(123: 1.1971) | VSYTCIPRK
(241: 1.5973) | GYPNINTYL
(116: 1.1822) | QTIDDYPPV
(35: 1.4284) |
| | 7 | TAAVKPLSY
(18: 1.8789) | TLASHPHYL
(208: 1.2381) | RVAEFLVVK
(198: 1.3425) | HYLHEANVF
(214: 1.6364) | EVPICSLEF
(185: 1.0192) |
| | 8 | SIMSLQIRY
(127: 1.1734) | FLFSPTDTL
(12: 1.3828) | RIKRNWQKK
(38: 1.3737) | IFMRLEDTI
(185: 1.4289) | SIIEKATRY
(200: 2.2008) |
| | 9 | YREILNEFY
(162: 1.6879) | FVAKYIPTI
(96: 1.3345) | LMMSCWSAR
(3: 1.1799) | LYTPALPPF
(17: 1.7705) | EVIEDLVVW
(321: 1.7072) |
| | 10 | SASNHKEFY
(11: 1.8707) | RMDVIGATV
(52: 1.1546) | EFYIYYLAK
(17: 0.7897) | QWTRRMHLI
(29: 1.3589) | SASNHKEFY
(11: 0.9535) |
| | 11 | LTDEKTCLK
(346: 1.7725) | FLTDEKTCL
(345: 1.2608) | QAFGRAIPK
(51: 1.2646) | TYAGTLPEM
(90: 1.0075) | YVSGISPTY
(83: 1.6128) |
| | 12 | LTDERTCLV
(508: 2.3650) | FLTDERTCL
(507: 1.2308) | RIQQLVLRK
(230: 1.3906) | LYIWNMPLL
(112: 1.9046) | TTITSTTKL
(445: 1.1733) |
| | 13 | LTDERTCLV
(721: 2.3650) | MLSAENLQL
(469: 1.2642) | KSLTNLYLK
(422: 1.3473) | EWSRVTSLL
(200: 1.6263) | EMKSLTNLY
(396: 1.8138) |
| | 14 | DLEEEVEEY
(115: 1.8614) | TLLEQYASL
(292: 1.2313) | LLEQYASLK
(293: 1.3401) | SFPPSPSLL
(2: 1.4148) | QVKELKVSY
(182: 1.2390) |
| | 15 | QTRVHPGLY
(116: 2.0525) | YLLDGDQLI
(71: 1.4042) | RSAPHHSRR
(226: 1.3101) | LFGAFLFAF
(388: 1.2731) | DVKESNAHV
(48: 1.1458) |
| | 16 | LVDTTAWRY
(1027: 3.6396) | MLWETVAAL
(290: 1.3564 | RTATARLHK
(248: 1.5070) | LFQRVLAPI
(982: 1.1324) | EAQDHSCFY
(628: 1.9956) |
| | 17 | KADTYVEEF
(82: 1.3354) | VLAVVVLLV
(10: 1.1790) | HLRGAATGK
(74: 1.4033) | DMATVFAYF
(151: 1.2555) | STVRLLVSF
(163: 1.4330) |
| | 18 | ATSNAASRY
(119: 3.2566) | TMADVLLYA
(135: 1.2997) | ATMADVLLY
(134: 1.3320) | QFLINSSSI
(2: 1.2187) | ATMADVLLY
(134: 1.7501) |
| | 19 | FTSGEISFY
(21: 3.4722) | YMNLISQSI
(1056: 1.2709) | LLYCRESRK
(1039: 1.6445) | AYLRELFPV
(702: 1.3356) | FTSGEISFY
(21: 2.3098) |
| | 20 | NTTTAVRGY
(27: 1.7205) | ILMWSFAAL
(204: 1.3025) | ALFVVMAMY
(211: 1.2263) | NWWILMWSF
(201: 1.5092) | NTTTAVRGY
(27: 1.5857) |
| | 21 | LASLLSSKY
(1096: 1.7120) | ALARYPLPV
(58: 1.3281) | ALASLLSSK
(1095: 1.5764) | VYILLTEFL
(1138: 1.6493) | HVARQLASY
(980: 2.0702) |
| | 22 | YMDPGAAGY
(201: 3.0231) | TLFPIDVTV
(220: 1.3367) | ALYTSIPVR
(288: 1.4227) | LFLLVIYAF
(35: 1.7091) | EAAHFLMAY
(155: 2.1321) |
| | 23 | CTGSSPSVY
(8: 2.2878) | VLIDYLLSM
(252: 1.4781) | TLASSAAVK
(184: 1.5850) | VYFTLPTAV
(15: 1.3233) | VLIDYLLSM
(252: 1.3831) |
| | 24 | LTAPVYMQY
(106: 3.2540) | LMFSLSQSL
(98: 1.2637) | RLTPFFQNY
(115: 1.2825) | LYRIDGTLI
(181: 1.3091) | ATGDQVSGY
(155: 1.9446) |
| | 25 | ISDTQVLLA
(264: 1.5818) | VLVGVVLGV
(539: 1.2310) | LVHAGIAGK
(486: 1.3287) | AYFVVPLEM
(356: 1.1485) | STVLRLFSF
(24: 1.4346) |
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