Neonatal Tetanus Immunity in Nigeria: The Effect of HIV Infection on Serum Levels and Transplacental Transfer of Antibodies

Table 4

The effect of HIV infection on maternal and newborn anti-tetanus antibody status and cord-maternal ratio (CMR).

HIV status	Anti-tetanus antibody status		OR	CI	value
	Seronegative (<0.1)	Seropositive (≥0.1)
Mothers
HIV positive	8	2	16.27	3.28–80.61	<0.001
HIV negative	30	122
Total	38	124
Newborns
HIV exposed	9	1	33.75	4.12–276.4	<0.001
Not exposed	32	120
Total	41	121
	Cord-maternal ratio
	Inefficient transfer (<1)	Efficient transfer (≥1)
Mothers
HIV positive	7	3	4.91	1.22–19.79	0.033
HIV negative	49	103
Total	56	106

HIV, human immunodeficiency virus; OR, odds ratio; CI, confidence interval; Fisher’s exact test.