Review Article
New Genetic Insights from Autoimmune Thyroid Disease
Table 3
Genes linked and/or associated with autoimmune thyroid disease.
| Gene symbol | Gene name | Chromosome location | Odds ratio |
| HLA | Major histocompatibility complex | 6p21 | 2.0–4.0 | CTLA4 | Cytotoxic T-lymphocyte-associated protein 4 | 2q33 | 1.5–2.2 | PTPN22 | Protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 1p13 | 1.4–1.9 | CD40 | CD40 molecule, TNF receptor superfamily member 5 | 20q11 | 1.3–1.8 | IL2RA (CD25) | Interleukin 2 receptor, alpha | 10p15 | 1.1–1.4 | FCRL3 | Fc receptor-like 3 | 1q23 | 1.1–1.3 | TG | Thyroglobulin | 8q24 | 1.3–1.6 | TSHR | Thyroid-stimulating hormone receptor | 14q31 | 1.4–2.6 |
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