Occult Central Lymph Node Metastasis in cN0 Papillary Thyroid Carcinoma Patients Undergoing TOETVA Procedure

Table 3

Analysis of factors affecting metastatic status of lymph nodes.

Variables	Nonmetastatic nodes	Metastatic nodes	Univariate analysis
	n = 208	n = 138	OR (95%)
Age
<29	34 (16.3)	37 (26.8)	0.5 (0.3–0.9)	0.02
≥29	174 (83.7)	101 (73.2)
Gender
Male	7 (3.4)	7 (5.1)	0.6 (0.2–1.9)	0.6
Female	201 (96.6)	131 (94.9)
Graves’ disease
No	2 (1)	2 (1.4)	0.7 (0.1–4.7)	0.7
Yes	206 (99)	136 (98.6)
Tumor diameter on US (mm)	7.1 ± 3.3 (2.6–20)	8.5 ± 0.3 (2.7–20)	1.1 (1.0–1.2)	0.00
Tumor location
Single lobe	200 (96.2)	129 (93.5)	1.7 (0.7–4.6)	0.3
Both lobes/isthmus	8 (3.8)	9 (6.5)
Surgical procedure
Total thyroidectomy	28 (13.5)	27 (19.6)	0.6 (0.4–1.1)	0.1
Conservative thyroidectomy	180 (86.5)	111 (80.4)
Central neck dissection
Both sides	24 (11.5)	24 (17.4)	0.6 (0.3–1.1)	0.12
One side	184 (88.5)	114 (28.6)
Tumor classification
T1a	169 (81.2)	98 (71)	1.8 (1.1–2.9)	0.03
≥T1b	39 (18.8)	40 (29)
Microscopic capsular invasion
No	153 (73.6)	103 (74.6)	0.9 (0.6–1.5)	0.82
Yes	55 (26.4)	35 (25.4)
Thyroiditis
No	168 (80.8)	117 (84.8)	0.8 (0.4–1.3)	0.3
Yes	40 (19.2)	21 (15.2)