Research Article
Circulating Irisin Levels Are Not Regulated by Nutritional Status, Obesity, or Leptin Levels in Rodents
Table 1
Body composition and biochemical and hormonal characteristics from the models studied.
| Group | Insulin (ng/mL) | Glucose (mg/dL) | Total cholesterol (mg/dL) | Fat mass (g) | Lean mass (g) |
| Low fat | 5.36 ± 1.08 | 18.51 ± 1.02 | 6.32 ± 0.40 | 56.53 ± 5.63 | 412.3 ± 4.0 | High fat | 9.07 ± 1.58 | 25.86 ± 0.96 | 7.14 ± 0.92 | 150.02 ± 23.04 | 435.1 ± 5.5 |
| Wild type mice | 2.01 ± 0.42 | 2.41 ± 0.13 | 0.78 ± 0.07 | — | — | ob/ob mice FED | 7.67 ± 1.63 | 4.40 ± 0.72 | 1.04 ± 0.03 | — | — | ob/ob mice FAST | 4.35 ± 0.85 | 1.94 ± 0.34## | 0.088 ± 0.04 | — | — | ob/ob mice FED + OB | 1.32 ± 0.97### | 3.24 ± 0.56 | 0.087 ± 0.02 | — | — |
| Rats FED | 1.11 ± 0.22 | 20.16 ± 2.09 | 5.09 ± 0.83 | 26.21 ± 0.88 | 175.6 ± 3.4 | Rats FAST | 0.09 ± 0.007 | 13.23 ± 0.71 | 8.20 ± 0.32 | 21.94 ± 0.71 | 163.5 ± 1.9 | Rats REFED | 1.13 ± 0.19## | 26.12 ± 0.78 | 6.14 ± 0.34# | 23.52 ± 1.13 | 166.6 ± 3.4 |
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Values are mean ± SEM of 7-8 animals per group. ; ; versus controls. ; ##; ### versus ob/ob FED and versus FAST 48 h.
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