CD226 Deficiency Alleviates Murine Allergic Rhinitis by Suppressing Group 2 Innate Lymphoid Cell Responses

Figure 3

CD226 on CD4⁺ T cells plays a limited role in AR development. (a) Serum levels of IgE and OVA-specific IgE detected using ELISA (). (b, c) Representative images and quantification of HE stained nose and lung sections (). (b)  μm and (c)  μm. (d) Representative images, absolute number, and frequency of nasal Th2 cells (CD4⁺ CCR4⁺ CCR6⁻) were detected using FCM (). AR: allergic rhinitis; OVA: ovalbumin; IgE: immunoglobulin E; ELISA: enzyme-linked immunosorbent assay, , , and .

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