Research Article

Predictive Values of Serum IL-33 and sST2 in Endotypes and Postoperative Recurrence of Chronic Rhinosinusitis with Nasal Polyps

Table 6

Unadjusted and adjusted multivariate logistic regression analysis of risk factors associated with CRSwNP recurrence.

FactorUnadjustedAdjusted
OR (95% CI)OR (95% CI)

Atopy1.854 (0.916-4.956)0.4191.592 (0.897-4.045)0.710
Allergic rhinitis1.529 (1.067-6.187)0.0071.396 (1.034-6.287)0.015
Asthma1.793 (1.158-5.287)0.0381.669 (0.911-3.892)0.092
B-EOS counts (106/L)1.378 (0.895-3.065)0.3871.258 (0.913-3.749)0.198
B-EOS percentage (%)2.162 (0.927-6.194)0.4671.867 (1.142-5.695)0.025
T-EOS counts2.367 (1.383-9.673)0.0022.198 (1.386-8.673)0.009
T-EOS percentage (%)2.980 (1.266-8.574)<0.0012.679 (1.197-9.266)0.001
Serum IL-33 level (pg/mL)3.769 (1.478-10.269)<0.0014.451 (1.313-11.672)<0.001
Serum ST2 level (ng/mL)3.687 (1.489-10.691)<0.0013.916 (1.195-12.764)<0.001

CRSwNP: chronic rhinosinusitis with nasal polyps; B-EOS: blood eosinophil; ST2: suppressor of tumorigenicity 2; OR: odds rate; CI: confidence interval. Adjusted for age, gender, smoking, BMI, atopy, allergic rhinitis, asthma, Lund-Mackay score, Lund-Kennedy score, and VAS score.