Research Article

Effects of CAR-T Cell Therapy on Immune Cells and Related Toxic Side Effect Analysis in Patients with Refractory Acute Lymphoblastic Leukemia

Table 3

Comparison of T lymphocyte subsets before and after treatment ().

GroupsCD3+ (%)CD4+ (%)CD8+ (%)CD4+/CD8+ (%)

Before treatment ()
CR+CRi patients treated for 1 month ()aaa
CR+CRi patients treated for 3 months ()a5aab
PD patients treated for 1 month ()
4.0108.3400.5408.700
0.010<0.0010.657<0.001

a compared with before treatment; b compared with CR+CRi patients treated for 1 month.