Potential Association of the Oral Microbiome with Trimethylamine N-Oxide Quantification in Mexican Patients with Myocardial Infarction

Figure 2

Relation of oral microbiota and trimethylamine N-oxide (TMAO) quantification in myocardial infarction patients according to cardiovascular risk factor group. (a) Trimethylamine N-oxide quantification by risk factor group (nmol/mL. p value, Mann–Whitney). Frequency of oral genera positively correlated to TMAO quantification by risk factor group, (b) Aggregatibacter and (c) Porphyromonas. (d) Alpha diversity analysis by Shannon index according to the risk factor group (p value, Mann–Whitney). (e) Principal coordinate analysis of beta diversity by Bray–Curtis index related to risk factor group (PERMANOVA, R² = 0.056, ). Blue (patients without standard risk factor “Non-SR”), red (patients with standard risk factor “SR”).

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