Research Article
Tanshinone IIA Alleviates Traumatic Brain Injury by Reducing Ischemia‒Reperfusion via the miR-124-5p/FoxO1 Axis
Figure 2
Tanshinone IIA reduces the I/R-induced inflammatory response and neuronal cell apoptosis. (a) TUNEL assay of apoptosis in rat cortical cells, scale bar = 100 μm; (b–d) ELISA analysis of IL-1β, IL-6, and TNF-α levels; (e) apoptosis-related proteins were examined by western blot; (f) RT-qPCR was used to analyze the mRNA expression of apoptosis related proteins. compared with the Sham group; #, ##, ###, compared with the MCAO group.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |