Aquaporin-4 Autoantibody Detection by ELISA: A Retrospective Characterization of a Commonly Used Assay

Table 1

Diagnosis by relative level of Aquaporin-4 detection by ELISA.

Diagnosis	, %
Low positive (3.0–7.9 U/mL),
Multiple sclerosis	10 (52.6)
Optic neuritis	2 (10.5)
Myelitis without LETM	2 (10.5)
Cyclic vomiting syndrome	1 (5.2)
Spinal cord infarct	1 (5.2)
Autoimmune thyroiditis	1 (5.2)
Migraine	1 (5.2)
Insufficient data	1 (5.2)
Moderate positive (8.0–79.9 U/mL),
NMOSD	9 (64.3)
Multiple sclerosis	2 (14.3)
Disseminated Lyme	1 (7.1)
Myelitis without LETM	1 (7.1)
Migraine	1 (7.1)
High positive (80 U/mL or higher),
NMOSD	14, (100)