Review Article

Hypoxia-Induced Oxidative Stress in Ischemic Retinopathy

Figure 2

Schematic showing the relationship of I/R, oxidative stress, and ROP. I/R causes overproduction of ROS/RNS. The resulting changes in levels of JAK/STAT, nitro-oxidation, and VEGF/IGF-1 contribute to pathogenesis of ROP.
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