Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo

<div>Effect of metformin on SOD and MDA levels in cultured MDCK cells treated with oxalate. (a) MDA levels of MDCK cells were treated with 1.6 mM sodium oxalate with or without 8 mM metformin for the indicated time points. (b) SOD activities of MDCK cells were treated with 1.6 mM sodium oxalate with or without 8 mM metformin for the indicated time points. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: Metformin Prevents Renal Stone Formation through an Antioxidant Mechanism In Vitro and In Vivo 