A “Weird” Mitochondrial Fatty Acid Oxidation as a Metabolic “Secret” of Cancer

Figure 2

Regulation of AMPK activity—role of ATP/ADP ratio and AMP level (adapted according to Hardie and Alessi [75]). The red blunt ends indicate the inhibition of a corresponding process. AMPK: 5AMP-activated protein kinase (dephosphorylated state—inactive); AMPK-P: 5AMP-activated protein kinase (phosphorylated state—active); FAO: fatty acid oxidation; FAS: fatty acid synthesis.