Polysaccharides from <i>Polygonatum cyrtonema</i> Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis

<div>PSP alleviated LPS-induced oxidative damage by regulating the Nrf2 signaling pathway. (a, b) show representative blots of Nrf2, HO-1, and quantification data for Nrf2/<i>β</i>-actin and HO-1/<i>β</i>-actin after LPS treatment. (c, d) show representative blots of Nrf2 and HO-1 and quantification data for Nrf2/<i>β</i>-actin and HO-1/<i>β</i>-actin after PSP treatment. (e) shows immunofluorescence images of Nrf2 and DAPI. (f) shows quantitative measurements of Nrf2<sup>+</sup> cells. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Polysaccharides from <i>Polygonatum cyrtonema</i> Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis 

Figure 4 | Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis 