Polysaccharides from <i>Polygonatum cyrtonema</i> Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis

<div>PSP inhibited LPS-induced NLRP3 pathway activation and glial cell activation. (a–d) show representative blots of NLRP3, ASC, caspase-1, and cleaved-caspase-1 and quantification data for NLRP3/<i>β</i>-actin, ASC/<i>β</i>-actin, caspase-1/<i>β</i>-actin, and cleaved-caspase-1/<i>β</i>-actin. (e, f) show representative blots of Iba1 and GFAP and quantification data for Iba1/<i>β</i>-actin and GFAP/<i>β</i>-actin. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Polysaccharides from <i>Polygonatum cyrtonema</i> Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis 

Figure 5 | Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression-Like Behavior in Mice by Inhibiting Oxidative Stress-Calpain-1-NLRP3 Signaling Axis 