Risk of Dementia in Patients with Depression or Parkinson’s Disease: A Retrospective Cohort Study

Table 2

Hazard ratio for dementia with different variables.

Variable	Adjusted HR^a (95% CI)
Age, years	1.10 (1.09–1.11)	<0.001
Gender
Female	1.00
Male	0.98 (0.81–1.19)	0.839
Hypertension	1.23 (1.00–1.51)	0.047
Diabetes mellitus	1.64 (1.30–2.07)	<0.001
Hyperlipidemia	0.70 (0.52–0.93)	0.014
Ischemic heart disease	0.95 (0.74–1.22)	0.693
PD/depression
Without PD/without depression	1.00
Without PD/with depression	1.55 (1.06–2.25)	0.024
With PD/without depression	3.29 (2.66–4.06)	<0.001
With PD/with depression	2.77 (1.88–4.08)	<0.001

Note. PD = Parkinson’s disease, HR = hazard ratio, % = percentage, CI = confidence interval, and  =  value. ^aAdjusted HR: adjusted for age, gender, hypertension, diabetes mellitus, hyperlipidemia, and ischemic heart disease.