Review Article

Lee Silverman Voice Treatment to Improve Speech in Parkinson’s Disease: A Systemic Review and Meta-Analysis

Table 1

Characteristics of the studies included in the present meta-analysis.

Study (year)Subject (N)Age (mean (SD))Sex M/FHYPD duration (years)InterventionIntervention/controlOutcomes

L O ramig 2001aI = 21I = 61.3 (11.4)I = 17/4I = 2.6 (0.6)I = 7.2 (5.4)I = LSVTI = 1 h/time, 4 times/week, for 4 weeksSPL, STSD
C = 12C = 63.3 (7.1)C = 7/5C = 2.2 (0.9)C = 5.0 (4.6)C = RETC = 1 h/time, 4 times/week, for 4 weeks

L O ramig 2001bI = 14I = 67.9 (9.0)I = 7/07I = 8.6 (6.3)I = LSVTI = 1 h/time, 4 times/week, for 4 weeksSPL
C = 14C = 69.8 (6.8)C = 7/07C = NO

LO ramig 1995I = 26I = 63.5 (11.5)I = 21/05I = 2.7 (0.7)I = 8.3 (9.3)I = LSVTI = 4 times/week, for 4 weeksSPL, STSD
C = 19C = 65.6 (8.9)C = 12/07C = 2.3 (0.8)C = 5.9 (4.7)C = RETC = 4 times/week, for 4 weeksMax duration

LO ramig 2018I = 22I = 64 (9)I = 14/8I = 2 (0.5)I = 5 (4)I = LSVTI = 1 h/day, 4 days/week, for 4 weeksSPL
C = 20C = 64 (9)C = 13/7C = NOC = 45 min/day, once/week, for 6–8 weeks

Arezzoo saffarian 2019I = 13I = 56.6 (4.70)I = 7/6I = 1.46 (0.49)I = LSVTI = 1 h/time, 4 days/week, for 4 weeksVHI
C = 13C = 57.8 (3.46)C = 5/5C = 1.20 (0.34)C = NO

LO ramig 1996I = 22I = 63.23 (11.87)I = 2.63 (0.6)I = 6.55 (5.25)I = LSVTI = 16 times/monthSPL
C = 13C = 65.31 (8.89)C = 2.25 (0.86)C = 4.77 (3.06)C = RETC = 16 times/month

Qi wu 2020I = 50I = 48.76 (7.21)I = 22/28I = 9.02 (3.71)I = LSVT + ConventionalI = 30–40/times, 2 times/day, 5 weeks + 0–40 min/time, 3 times/day, 3 weeksVHI, UPDRS-III, speech intelligibility
C = 50C = 48.76 (7.21)C = 20/20C = 9.68 (4.11)C = ConventionalC = 30–40 min/time, 3 times/day, 3 weeks

Haiyu tang 2016I = 32I = 69.75 (4.35)I = 17/19I = 2.02 (0.54)I = 4.52 (3.26)I = LSVT + ConventionalI = 40–60 min/time, 4 times/weeks, 12 weeks + 1 h/time, 4 times/week, 12 weekVHI, WAB, speech intelligibility
C = 32C = 68.45 (4.62)C = 15/13C = 2.05 (0.48)C = 4.46 (3.43)C = ConventionalC = 40–60 min/time, 4 times/week, 12 weeks

Meifang yang 2017I = 49I = 66.83 (2.89)I = 27/22I = 2.11 (0.27)I = 5.12 (0.67)I = LSVTI = 1 h/time, 4 times/week, 12 weeksVHI, WAB
C = 49C = 65.82 (2.56)C = 25/24C = 2.09(0.34)C = 5.52(0.16)C = ConventionalC = 1 h/time, 4 times/week, 12 weekSpeech intelligibility

Geralyn schulz 2021I = 20I = 67I = 15/15I = 2.13I = 4.89I = LSVTSPL
C = 18C = 63.5C = 11/07C = 2.14C = 4.64C = NO

I: intervention; C: control; LSVT: Lee Silverman voice treatment; RET: high-effort respiratory treatment program; NO: no treatment; SPL: sound press level; STSD: semitone standard deviation; Max duration: maximum duration; PDQ-39 communication: Parkinson’s disease questionnaire-39 communication; VHI: voice handicap index; WAB: western aphasia battery.