Research Article

DA5-CH and Semaglutide Protect against Neurodegeneration and Reduce α-Synuclein Levels in the 6-OHDA Parkinson’s Disease Rat Model

Figure 5

Effects of drugs on 6-OHDA-induced changes in α-synuclein expression in the substantia nigra. (a) Analysis of α-syn monomers (b) and oligomers expression in SNpc. Each group represents the means ± SEM of 5 rats per group; (one-way ANOVA followed by the Tukey multiple comparisons test;;;;. The legend relates to both (a) and (b) graphs. (c) Sample western blot. Sham-Sal;6-OHDA + Sal;6-OHDA + Sema; 6-OHDA + DA5-CH.
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