The Role of Muscle Strength in the Sit-to-Stand Task in Parkinson’s Disease
Table 1
Clinical and demographic features between patients with abnormal and normal sit-to-stand tasks.
PD patients with abnormal STS task, n = 20 (%)
PD patients with normal STS task, n = 70 (%)
value
Age at evaluation (years)
70.9 ± 8.1
67.2 ± 10.7
0.160
Sex (male)
11 (55)
40 (57)
0.865
PD time since onset (years)
9.55 ± 9.03
7.02 ± 5.73
0.139
MDS-UPDRS-III total score
47.95 ± 13.77
31.07 ± 15.01
<0.001
Leg rigidity
1.97 ± 0.88
1.45 ± 0.92
0.053
Leg bradykinesia
1.86 ± 0.74
1.09 ± 0.83
<0.001
R Leg bradykinesia
1.55 ± 0.90
1.00 ± 0.95
0.015
L Leg bradykinesia
2.17 ± 0.71
1.23 ± 0.92
<0.001
Gait
3.10 ± 0.64
1.46 ± 0.93
<0.001
Freezing
2.10 ± 1.80
0.40 ± 0.90
<0.001
Postural stability
2.10 ± 0.86
1.33 ± 0.99
<0.001
Leg tremor
0.45 ± 0.77
0.30 ± 0.63
0.405
Modified Hoehn and Yahr stage
4.20 ± 0.76
3.11 ± 1.63
<0.001
LEDD
808.7 ± 618.6
597.2 ± 606.5
0.174
Orthostatic hypotension
8 (40)
18 (25.7)
0.214
Weakness and allied sensations
Affected patients
19 (95)
43 (61.4)
0.004
Severity by VAS (0–10)
7.35 ± 2.45
4.33 ± 3.64
<0.001
Clinical examination (MRC)
Right hip flexion
4.55 ± 0.51
4.87 ± 0.34
0.014
Right leg extension
4.80 ± 0.41
4.97 ± 0.17
0.082
Right foot plantar flexion
5.00 ± 0.00
5.00 ± 0.00
—
Left hip flexion
4.55 ± 0.51
4.87 ± 0.36
0.014
Left leg extension
4.70 ± 0.47
4.97 ± 0.17
0.019
Left foot plantar flexion
5.00 ± 0.00
5.00 ± 0.00
—
Quantitative assessments (kg)
Right hip flexion
12.12 ± 2.80
14.06 ± 2.79
0.290
Left hip flexion
13.24 ± 2.04
14.36 ± 2.83
0.072
Right hip extension
10.57 ± 5.20
12.76 ± 4.49
0.078
Left hip extension
9.83 ± 6.25
12.62 ± 4.35
0.030
LEDD, levodopa equivalent daily dose; MDS-UPDRS-III, Movement Disorders Society Unified Parkinson’s Disease Rating Scale part III; MRC, Medical Research Council; VAS, visual analog scale. OH is defined as drop in the systolic blood pressure ≥20 mmHg or diastolic blood pressure ≥10 mmHg.
