Single-Cell Analyses Reveal Necroptosis’s Potential Role in Neuron Degeneration and Show Enhanced Neuron-Immune Cell Interaction in Parkinson’s Disease Progression

<div>Analysis of hub transcription factors driving the necroptosis in degenerated neurons. (a) Regulated transcription factors were obtained from DEGs; 23 TFs were identified. (b) PPI network of the TFs and DEGs in degenerated neurons. NRGs were centered. (c) PPI network of the NRGs and their related TFs in degenerated neurons. TFs were centered.</div>

Parkinson’s Disease

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Figure 7

Figure 7: Single-Cell Analyses Reveal Necroptosis’s Potential Role in Neuron Degeneration and Show Enhanced Neuron-Immune Cell Interaction in Parkinson’s Disease Progression 

Figure 7 | Single-Cell Analyses Reveal Necroptosis’s Potential Role in Neuron Degeneration and Show Enhanced Neuron-Immune Cell Interaction in Parkinson’s Disease Progression 