Sex Differences in the Allele Distribution of PGLYRP2 Variant rs892145 in Parkinson’s Disease

Table 2

Results from the genetic analysis.

Gene	SNP	Allele	Control % (n)	PD % (n)	OR (95% CI)	value
PGLYRP2	rs892145	A	63.2 (733)	62.6 (617)	1.01 (0.85–1.21)	0.96
		T	36.8 (427)	37.4 (369)
	Female strata	A	61.2 (382)	67.9 (250)	0.76 (0.58–0.99)	0.04
		T	38.8 (242)	32.1 (118)
	Male strata	A	65.2 (347)	59.4 (367)	1.29 (1.01–1.64)	0.04
		T	34.7 (185)	40.7 (251)
	rs959117	T	51.4 (588)	50.2 (494)	1.05 (0.88–1.24)	0.61
		C	48.6 (556)	49.7 (490)
PGLYRP4	rs10888557	G	90.9 (918)	91.2 (598)	1.01 (0.71–1.43)	0.96
		C	9.1 (92)	8.8 (58)

SNP: single nucleotide polymorphism, n: number of alleles, PD: Parkinson’s disease, OR: odds ratio, CI: confidence interval. Data were analyzed with logistic regression with sex as a covariate for the entire cohort and stratified by sex as indicated for rs892145.