A Dual GLP-1/GIP Receptor Agonist Is More Effective than Liraglutide in the A53T Mouse Model of Parkinson’s Disease

Figure 4

Testing spontaneous motor activity in the open field test. DA5-CH improved exploratory, anxiety, and motor activities better than liraglutide. (a–c) The percentage of residence time in the central area, the total numbers of rearing, and the total distance moved for each group. (d) Track examples of the open field test for each group of mice.  < 0.05,  < 0.01, and  < 0.001 compared to the control group; ^# < 0.05 and ^## < 0.01 compared to the A53T saline-treated group. N = 12 per group.

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