Research Article

The Neuroprotective Effect of Isotetrandrine on Parkinson’s Disease via Anti-Inflammation and Antiapoptosis In Vitro and In Vivo

Figure 2

Effect of ITD on 6-OHDA-induced locomotor deficiency in zebrafish. Zebrafish larvae were pretreated with 200, 100, or 10 μM ITD from 9 h postfertilization (hpf) to 5 dpf and then challenged with 250 μM 6-OHDA from 2 to 5 dpf. The locomotor activity of zebrafish was measured at (a) 5 dpf and (b) 6 dpf. The upper panel shows a representative pattern, and the lower panel shows average results. Data are presented as mean ± SEM (n = 16). significantly different from the control group; #significantly different from the 6-OHDA group; .
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