Clinical Study

The Small-Conductance Ca2+-Activated Potassium Channel, Subtype SK3, in the Human Myometrium Is Downregulated in Early Stages of Pregnancy

Figure 2

The mRNA levels of SK3 in nonpregnant women (NP), preterm deliveries (PT), pregnancy at term not laboring (TNL), and pregnancy at term laboring (TL) expressed relative to β-actin, (a). Data is presented as mean ± SEM ( ( ), ( ), ( ), and ( ) for NP, PT, TNL, and TL, resp.). *** (versus NP). Protein expression of SK3 in nonpregnant (NP) and pregnant at term not laboring (TNL) (b). Blots show the expected molecular weight of ~70 kDa and ~43 kDa for SK3 and β-actin respectively ( for both groups). (c) Accumulated measurements of protein expression from both groups of patients. All data are ratio to β-actin in the same sample. Data is presented as mean ± SEM. ( and for NP and TNL, resp.). Asterisk ( ) represents significant difference from NP patients ( ).
584717.fig.002a
(a)
584717.fig.002b
(b)
584717.fig.002c
(c)