The Potential Role of Hemopexin and Heme Oxygenase-1 Inducer in a Model of Sepsis

Figure 4

The number of thrombi per field. Sections of the livers and lungs from control rats (CG), CLP rats with cecal ligation induced sepsis (CLP), CLP rats pretreated with hemin (CLP + Hm), or CLP rats pretreated with hemopexin (CLP + HPx). Sections were stained with H&E and examined by light microscopy. The numbers of thrombi were counted in 10 randomly selected fields (magnification ×40) per organ and the mean number in the 10 fields was taken. The data were analyzed using one-way ANOVA test, , and expressed as mean ± SEM ( 7–12 per group). versus CG, versus CLP group, and versus CLP + Hm group.