PPAR-γ Activation Alleviates Osteoarthritis through Both the Nrf2/NLRP3 and PGC-1α/Δψ_m Pathways by Inhibiting Pyroptosis

Table 1

Histochemical assessment of rat articular cartilage changes.

Grade	S-O staining
0	Uniform staining throughout articular cartilage
1	Loss of staining in superficial zone of hyaline cartilage <50% the length of the condyle or plateau
2	Loss of staining in superficial zone of hyaline cartilage ≥50% the length of the condyle or plateau
3	Loss of staining in the upper 2/3’s of hyaline cartilage <50% the length of the condyle or plateau
4	Loss of staining in the upper 2/3’s hyaline cartilage ≥50% the length of the condyle or plateau
5	Loss of staining in all the hyaline cartilage <50% the length of the condyle or plateau
6	Loss of staining in all the hyaline cartilage ≥50% the length of the condyle or plateau