Research Article

Interleukin-1β Enhances Umbilical Cord Mesenchymal Stem Cell Adhesion Ability on Human Umbilical Vein Endothelial Cells via LFA-1/ICAM-1 Interaction

Figure 5

Schematic diagram of IL-1β signaling pathway in MSC adhesion to HUVECs. The schematic diagram depicts the proposed role of IL-1β signaling pathway in MSC adhesion to HUVECs. The process of cell adhesion is initiated by IL-1β through p38 MAPK; induced expression of LFA-1 in MSCs enhances the cell adhesion to IL-1β-induced ICAM-1 in HUVECs.