Research Article

Clinical Factors Associated with Sperm DNA Fragmentation in Male Patients with Infertility

Table 5

The attributes of the clinical parameters associated with DNA damage in the multiple linear regression.

ParameterStandardized partial regression coefficient value95% confidence interval
Lower limitUpper limit

Model 1
 Chronic alcohol use 
 (+) versus (−)
0.2744 0.0394*0.2922 11.1788
 Serum FSH 
 ≥5.6 versus <5.6 (mIU/mL)
0.1429 0.2466 −2.1513 8.1519
 Normal sperm morphology 
 ≥1.5 versus <1.5 (%)
−0.0557 0.6813 −6.8560 4.5226
 Sperm progressive motility 
 ≥33.0 versus <33.0 (%)
−0.4864 0.0008*−15.9232 −4.5046
 Total sperm count 
 ≥97.0 versus <97.0 (million)
−0.0605 0.6369 −6.6348 4.1036
 Linearity 
 ≥0.4 versus <0.4
−0.0471 0.7221 −6.5417 4.5696
 Proportion of vacuolated sperm 
 ≥19.0 versus 19.0 (%)
0.0669 0.5782 −3.6395 6.4395
Model 2
 Chronic alcohol use 
 (+) versus (−)
0.3069 0.0068*1.9444 11.5084
 Sperm progressive motility 
 ≥33.0 versus <33.0 (%)
−0.5381<0.0001*−16.5970−7.0193

ALH: amplitude of lateral head displacement; FSH: follicle-stimulating hormone; statistically significant.