Oxidative Transformation of Controlled Substances by Manganese Dioxide

Table 1

Physicochemical properties of ketamine, methamphetamine, morphine, and codeine.

	Molecular formula	Molecular weight (g/mol)	pKa	Solubility (mg/mL)	Structure
Ketamine	C13H16ClNO	237.7	7.5^b	250
Methamphetamine	C10H15N	149.2	9.9^a	NA
Morphine	C17H19NO3	285.3	9.85^b (phenol group)	60
Codeine	C18H21NO3	299.4	9.8^b	434.8

[19], ^b[20].