The Number of Grafted Fragments Affects the Outcome of Testis Tissue Xenografting from Piglets into Recipient Mice
Table 2
Correlations between the mouse body weight, average graft weight, or total graft weight and characteristics of testis tissue xenografts at the time of sacrifice at 8 months postgrafting.
Mouse body weight (g)
Average graft weight (mg)
Total graft weight (mg)
r
P
r
P
r
P
Mouse body weight (g)
—
—
0.2
.3
0.3
.1
Graft recovery rate (%)
0.02
.9
0.3
.1
0.3
.1
Average graft weight (mg)
0.2
.3
—
—
0.8
.0001
Total graft weight (mg)
0.3
.1
0.8
.0001
—
—
Tubular diameter (m)
0.5
.002
0.3
.1
0.3
.1
Tubular density (mm2)
0.1
.4
0.01
.9
0.04
.8
Vesicular gland index (%)
0.1
.4
0.4
.02
0.4
.02
Spermatozoa (% tubules)
0.07
.1
0.5
.01
0.5
.001
Elongated spermatids (% tubules)
0.3
.1
0.5
.002
0.7
.0001
Round Spermatids (% tubules)
0.3
.07
0.5
.001
0.6
.0004
Spermatocytes (% tubules)
0.2
.3
0.1
.6
0.01
.96
Spermatogonia (% tubules)
0.01
.97
0.5
.01
0.4
.01
Sertoli-cell-only (% tubules)
0.4
.02
0.5
.01
0.6
.0002
Degenerated (% tubules)
0.1
.6
0.2
.3
0.3
.1
Pearson’s correlation coefficients (r) were calculated for the combined data from four different groups of recipient mice grafted with different numbers of porcine testis tissue fragments, and the grafts evaluated at 8 months postgrafting for spermatogenic development. Correlation coefficients were considered significant when .
