Research Article

Novel Phytosomal Formulation of Emblica officinalis Extracts with Its In Vivo Nootropic Potential in Rats: Optimization and Development by Box-Behnken Design

Table 3

ANOVA results showing the effect of independent variables on the response studied.

SourceSum of squaresdfMean squareF value value prob > F

Model131.087914.56530.009<0.0001Significant
A: phopholipid: drug ratio3.51113.5117.2340.0311
B: temperature49.005149.005100.967<0.0001
C: time35.701135.70173.557<0.0001
AB2.8912.895.9540.0447
AC0.72210.7221.4890.2619
BC4.4114.419.0860.0195
A21.99011.9904.1000.0825
B21.00111.0012.0620.1942
C231.553131.55365.010<0.0001
Residual3.39870.485
Lack of fit1.937530.6461.7690.2918Nonsignificant
Pure error1.4640.365
Cor total134.48416