Research Article

Hydroxychloroquine: Pharmacokinetics and Toxicity

Table 3

Main characteristics of extreme outliers for COVID-19 patients.

PatientSexDayAge (years)HCQ serum level (μg/mL)Clinical outcomeDrug-related adverse eventDeath

1F2650.804GoodNoNo
7F16371.452GoodNoNo
9F17$891.32PoorNoYes

Patient already taking HCQ before COVID-19 for lupus. $Treatment duration with HCQ was extended due to persistence of viral shedding and acute respiratory distress.