Risk factors included age, sex, and APOE ε4 allele status; deregulated miRNA panel was exclusive of miR-3065-5p. MiRNAs in this study were derived from unspecified extracellular vesicles. †Young-onset AD occurred before the age of 65 years; late-onset AD occurred after the age of 65 years. ††Only validation cohorts are listed in this table. Abbreviations: AD: Alzheimer’s disease; ALS: amyotrophic lateral sclerosis; AUC: area under the curve; CSF: cerebrospinal fluid; DAT: dementia of Alzheimer type; DLB: dementia with Lewy bodies; MCI: mild cognitive impairment; miR/miRNA: microRNA; NCs: normal controls; NDDs: neurodegenerative diseases; PD: Parkinson’s disease; piR: piwi-interacting RNA; pts: patients; RT-qPCR: quantitative reverse transcription polymerase chain reaction.