Lower Urinary Tract and Gastrointestinal Dysfunction Are Common in Early Parkinson’s Disease

Table 4

Regression model predicting a SCOPA-AUT score of ≥10 in patients with early PD (not including MDS-UPDRS parts I, II, and total).

Variable	Coefficient (β)	SE	Exp (β)	95% CI of Exp (β)	value
Intercept	−4.22	0.79	—	—	—
Fatigue	1.45	0.39	4.28	2.01 to 9.10	<0.001
pbRBD	1.00	0.25	2.71	1.65 to 4.45	<0.001
QUIP-RS	0.88	0.40	2.42	1.41 to 4.14	0.001
ESS	0.63	0.31	1.88	1.03 to 3.44	0.039
Current age	0.05	0.01	1.05	1.02 to 1.07	<0.001
MDS-UPDRS part III	0.02	0.01	1.02	1.00 to 1.05	0.062

SCOPA-AUT: Scales for Outcomes in Parkinson’s Disease-Autonomic dysfunction; PD: Parkinson’s disease; CI: confidence interval; pbRBD: probable REM Sleep Behavior Disorder; QUIP-RS: Questionnaire for Disorders in Parkinson’s Disease—Rating Scale; ESS: Epworth Sleepiness Scale; MDS-UPDRS: Movement Disorder Society-Unified Parkinson’s Disease Rating Scale; SE: standard error. The regression model was statistically significant (), explained 23.4% of the variance in SCOPA-AUT scores of ≥10, and correctly classified 70.2% of cases.