Predicting Cognitive Decline in Parkinson’s Disease with Mild Cognitive Impairment: A One-Year Observational Study

Table 1

Comparison of demographic and clinical characteristics between PD-MCI and AD-MCI groups.

Group	PD-MCI N = 35	AD-MCI N = 39	value
Cognitive decline (%)	10 (28.6)	3 (7.7)	0.030
Median age of visit	69.0	70.0	0.451
Male (%)	17 (48.6)	23 (59.0)	0.484
Education (year)	8.57	7.56	0.268
BMI	23.87	24.04	0.838
MMSE	25.80	24.92	0.285
CDR-SB	1.59	1.83	0.343
CVLT-SF immediate recall	5.47	5.46	0.985
CVLT-SF delayed recall	4.44	4.51	0.900
CVLT-SF recognition	5.56	5.13	0.470
TCF copy	31.26	30.00	0.445
TCF recall	13.98	13.76	0.912
JLO	13.70	13.37	0.703
Forwards digit recall	7.03	7.41	0.298
Backward digit recall	3.85	4.24	0.272
Trail making test A	30.08	23.33	0.150
Trail making test B	71.46	59.41	0.160
Verbal fluency animal	12.24	12.15	0.927
Boston naming Test	23.53	21.72	0.112
CTP Recall	13.13	14.08	0.516
CTP recognition	16.26	17.62	0.288
GDS-15 > 5 (%)	8 (24.2)	6 (15.4)	0.384
PSQI > 5 (%)	16 (51.6)	19 (48.7)	1.000
Barthel index	93.68	99.36	0.053
IADL	19.88	23.00	0.005
Tinetti balance	14.10	15.56	0.026
Tinetti gait	11.00	11.85	0.033
Walking speed (m/s)	0.822	0.878	0.267
Cadence (steps/min)	98.49	97.56	0.785
Stride length (cm)	66.06	67.72	0.765
TUG total (s)	19.97	15.72	0.080
TUG sit-to-stand (s)	1.94	1.68	0.034
TUG mid-turnings (s)	3.08	2.58	0.258
TUG end-turnings (s)	3.00	2.13	0.023
TUG stand-to-sit (s)	2.54	2.57	0.922

Statistically significant values compared between the groups .