Research Article

Handgrip Strength and Anthropometry in Parkinson’s Disease at Diagnosis

Table 5

Multiple linear regression models, B-value, and value in patients (N = 75) and controls (N = 24) for ECW/ICW ratio, TBW (ECW + ICW, l), FFMI, and FM (%). Interaction between cortisol and phosphate is excluded (not significant).

ECW/ICW ratioTBWFFMIFM (%)
Cases N  = 75Controls N  = 24Cases N  = 75Controls N  = 24Cases N  = 75Controls N  = 24Cases N  = 75Controls N  = 24

Age, years0.007 (<0.001)0.007 (0.054)−0.141 (0.033)−0.382 (<0.001)−0.006 (0.823)−0.036 (0.303)0.135 (0.041)0.146 (0.317)
BMI (kg/m2)−0.004 (0.327)−0.002 (0.577)0.515 (<0.001)0.880 (<0.001)0.324 (<0.001)0.413 (<0.001)0.615 (<0.001)0.705 (0.002)
Sex, M = 0 F = 10.055 (0.121)0.022 (0.627)−9.175 (<0.001)−9.515 (<0.001)−1.961 (<0.001)−1.621 (0.003)7.961 (<0.001)6.169 (0.006)
P-cortisol (μmol/l)0.000 (0.662)0.000 (0.239)−0.010 (0.019)0.000 (0.978)−0.003 (0.040)−0.001 (0.675)0.007 (0.090)0.006 (0.479)
P-phosphate (mmol/l)−0.052 (0.652)−0.124 (0.469)1.159 (0.759)6.051 (0.162)−0.522 (0.727)0.346 (0.847)−1.362 (0.713)−1.852 (0.806)
UPDRS-III0.005 (0.006)−0.154 (0.007)−0.047 (0.034)0.052 (0.348)
R20.3790.3180.6410.9420.5580.8870.5620.613

UPDRS = Unified Parkinson’s Disease Rating Scale. BMI = body mass index (kg/m2). ECW = Extracellular Water, l. ICW = intracellular water, l. TBW = total body water (ECW + ICW). FFMI = fat-free mass index (kg/m2). FM (%) = fat mass percent. The significance level is 95% CI p<0.05.