Research Article

Predictive Value of Nasal Nitric Oxide and Serum NOS2 Levels in the Efficacy of Subcutaneous Immunotherapy in Pediatric Patients with Allergic Rhinitis

Table 5

ROC results of different parameters for early predicting SCIT efficacy.

VariablesAUC (95% CI) valueCut-off valueSensitivitySpecificity

Serum NOS2 (IU/ml)0.759 (0.645-0.873)<0.0015.584.1%66.7%
Nasal NO (ppb)0.716 (0.596-0.837)0.003681.065.1%76.2%
Combined0.787<0.001

ROC: receiver operating characteristics; SCIT: subcutaneous immunotherapy; AUC: area under the curve; CI: confidence interval; ppb: parts per billion.