The Scientific World Journal

Research Article

NMR Spectroscopy of Human Eye Tissues: A New Insight into Ocular Biochemistry

Table 1

Statistical significance of biochemical differences between the eye tissues.
MetaboliteHomogeneityNormalityType of analysisCornea-CB***Cornea-iris***Cornea-lens***Cornea-retina***CB-retina***Iris-retina***Lens-retina***
Ac−*+**AW−−−−−−−
Ala+*−**KW++++−−−
Arg−+AW−−−−−−−
Asc++A++−+−−+
ATP−+AW++++−−−
But++An/an/an/an/a−−n/a
Ch−+AW−−n/a+−−n/a
Cr+−KW++++−−−
For−+AW++++−−−
GPC++A+++n/an/an/an/a
Gln−+AW+−−++−−
Glc−+AWn/an/a+n/an/an/an/a
Glu−+AWn/an/a++n/an/a−
GMP−+AWn/an/an/an/a−+n/a
GSH−−−n/an/an/an/an/an/an/a
His++A−n/a−n/an/an/an/a
h-Tau++An/an/an/an/an/an/an/a
Ile+−KW+−++−−+
Lac−+AW++−+−−+
Leu−+AW++−−−−−
Met++An/an/an/a−n/an/an/a
m-In−+AW++++++−
P-Ch−+AWn/an/an/an/a−−−
P-Cr++An/an/an/an/a−−+
Phe++A−−−−−−−
Su+−KW+n/a+−+n/a−
Tau−+AW−−−++−+
Tyr−+AW−−+−−−−
Val++A−−−−−−−
homogeneity of the groups (+/−, yes/no); **normality of the distribution within the groups (+/−, yes/no); ***statistical significance of differences between the groups of samples (+/−, positive/negative); A: one-way analysis of variance (ANOVA); AW: ANOVA with method of Welch for treating unequal variances; K: the Kruskal-Wallis test; n/a: not applicable due to the lack of data for one or both groups of samples; CB: ciliary body. For metabolite labels see legend for Figure 1.